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Search Results for " bet bromodomain inhibitor 3 "

6

Compounds

Cat No. Product Name Synonyms Targets
T79084 BET bromodomain inhibitor 3 Epigenetic Reader Domain
BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT. It is utilized in research related to contraception, cancer, and heart disease [1].
T6032 Birabresib OTX-015,OTX015 (MK 8628/Birabresib),MK-8628 Epigenetic Reader Domain
Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4 with potential antineoplastic activity.
T4697 ABBV-744 ABBV744 Epigenetic Reader Domain , HIV Protease
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.
T22345 INCB054329 INCB-054329,INCB-54329,INCB-54329 Epigenetic Reader Domain
INCB054329, a structurally distinct bromodomain and extraterminal domain (BET) inhibitor, inhibits BRD2-BD1, BRD2-BD2, BRD3-BD1, BRD3-BD2, BRD4-BD1, BRD4-BD2, BRDT-BD1 and BRDT-BD2 with IC50 values of 44 nM, 5 nM, 9 nM, ...
T1972 GSK-5959 Epigenetic Reader Domain
GSK-5959 is an effective, specific and cell permeable BRPF1 bromodomain inhibitor (IC50: ~80 nM). The selectivity of GSK-5959 for BRPF1 is >100-fold over a panel of 35 other bromodomains, including BRPF2/3 and BET family...
T69506 DBRD4-BD1
dBRD4-BD1 is a selective BRD4 bromodomain inhibitor. dBRD4-BD1 can selectively degrade BRD4 (DC50 = 280 nM). Notably, dBRD4-BD1 upregulates BRD2/3, a result not observed with degraders using pan-BET ligands. Designing BR...
TargetMol